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You should take a look, and see what you think. All of the classical measures of oxidative stress are higher in the mole-rat. It slows things down and sort of sets up an artificial step in the process. archives, you'll find more on the significance of Notch when working with embryonic stem cells. How are the mole-rats getting away with it? I think that there should be a massive regenerative medicine project, a nationwide effort to really try to accelerate these technologies to patients. Similarly, diabetes may harm cognition by either leading to artery disease or via direct effects of the hormone insulin on brain cells. It is possible, they reasoned, that the mole-rat suffers greater oxidative stress, but its physiology had somehow prevented damage from occurring. As such, and unfortunately, alagebrium appears to work on AGEs that are much more common in old rats than in old people. Wikipedia, the free encyclopedia explains. A complicated thing, metabolism. Beyond that fact, there are many examples in nature of systems that are, in effect, immortal until ended by violence or radical change in their ecosphere. You should take a look, and see what you think. The issue at hand right now is that the technologies are there. Wikipedia, the free encyclopedia explains. Coverage focuses on energy markets, base metals. Once the animal expended that number of calories, the grim reaper was on the doorstep. archives, you'll find more on the significance of Notch when working with embryonic stem cells. Wikipedia, the free encyclopedia explains. Some researchers complain that the licensing process slows their work down, while others say it is prohibitively expensive. Old-style drugs can't get much better - but gene therapy has hardly even started. There was no difference in life span between the two runner groups, even though one expended more energy. Encourage the people you know to pitch in and make a difference to the future of health and longevity! Competition is the only incentive process that leads to better, cheaper, more effective products. In multiple sclerosis, Notch sets off an autoimmune attack against the brain via the overproduction of certain immune cells. They are known as AGE-breakers. Over the years, the theory has become much more sophisticated, but metabolic rate and aging have remained linked . |